[2] Cheltenham 1-0 Leyton Orient [10] 2021-04-10 14:00
Stadium: Jonny-Rocks Stadium Round: 41
Referee: Thomas Bramall Home Manager: Michael James Duff Away Manager: Joel Joshua Frederick McAnuff
Head to Head
| Anglicko - League 2 | 2020/10/03 14:00 | Leyton Orient v Cheltenham | W | 0-2 |
| Anglicko - League 2 | 2020/02/15 15:00 | Cheltenham v Leyton Orient | W | 2-1 |
| Anglicko - League 2 | 2019/08/03 14:00 | Leyton Orient v Cheltenham | L | 1-0 |
| Anglicko - League 2 | 2017/02/25 15:00 | Leyton Orient v Cheltenham | W | 0-1 |
| Anglicko - League 2 | 2016/08/06 14:00 | Cheltenham v Leyton Orient | D | 1-1 |